GITR / TNFRSF18 Proteïne (mFc dag)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GITR, also known as TNFRSF18 (CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
AITR Protein; Gitr Protein; Tnfrsf18 Protein
NP_033426.1
Mouse
Mouse
MFc-Tag
See Datasheet send with the product
< 1.0 EU per μg protein as determined by the LAL method.
> 95 % as determined by SDS-PAGE.
Data not available
368
Lyophilized or frozen liquid
PBS, pH 7.4
See Datasheet
41 kDa
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
HEK 293 cells
Beschrijving
GITR, also known as TNFRSF18 (CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role i
Specificaties
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