GITR/TNFRSF18 Proteïne, Muis, Recombinant (hFc & His)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Tumor necrosis factor receptor superfamily member 18 (Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA, isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.
Ice Packs
-20°C
Beschrijving
GITR/TNFRSF18 Proteïne, Muis, Recombinant (hFc & His) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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