Glaxolide-d6 (mengsel van diastereomers) (>80%)

Galaxolide-d6 (mixture of diastereomers) (>80%) is the deuterium labeled Galaxolide. Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), trigger oxidative stress and genotoxicity, and induce EROD and GST (Glutathione S-transferase) enzyme activity[1][2].

12352005

Estrogen Receptor/ERR; Glutathione S-transferase; Isotope-Labeled Compounds

Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Metabolism-protein/nucleotide metabolism

Endocrinology

CC1(C)C(C)C(C)(C)C2=C1C=C3C(C([2H])(C([2H])([2H])[2H])C([2H])([2H])OC3)=C2

C18H20D6O

264.44

[1]Jo-Anne E Cavanagh, et al. Assessment of endocrine disruption and oxidative potential of bisphenol-A, triclosan, nonylphenol, diethylhexyl phthalate, galaxolide, and carbamazepine, common contaminants of municipal biosolids. Toxicol In Vitro. 2018 Apr:48:342-349.|[2]Friday O Ehiguese, et al. Potential of environmental concentrations of the musks galaxolide and tonalide to induce oxidative stress and genotoxicity in the marine environment. Mar Environ Res. 2020 Sep:160:105019.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W100026S/

Isotope-Labeled Compounds

No Development Reported