GLI1 Mouse Monoklonale Antilichaam [Kloon ID: LBI2D5E2]

This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Carrier-free (BSA/glycerol-free) Purified GLI1 mouse monoclonal antibody, clone LBI2D5E2

GLI

Homo sapiens GLI family zinc finger 1 (GLI1), transcript variant 1, mRNA.

2735

P08151

Unconjugated

Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

WB 1:2000, IHC 1:150

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

GLI1

https://www.ncbi.nlm.nih.gov/gene/?term=2735

https://www.uniprot.org/uniprot/P08151