GLIPR1 Antilichaam

The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1) . GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer (2) . The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary (3) .

11010

P48060

NP_006842

Human, Mouse

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

GLIPR1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1308 - Human Small Intestine Tissue Lysate

1 mg/mL

GLIPR1 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

GLIPR1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

GLIPR1 antibody is human and mouse reactive. At least two isoforms of GLIPR1 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

GLIPR1

Cat. No. 11-801 - Human Small Intestine Tissue Slide

GLI pathogenesis-related 1

Homo sapiens

Murphy EV, Zhang Y, Zhu W, et al. The human glioma pathogenesis-related protein is structurally related to pathogenesis-related proteins and its gene is expressed specifically in brain tumors. Gene 1995; 159:131-5.

Ren C, Li L, Yang G, et al. RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer. Cancer Res. 2004; 64:969-76.

Ren C, Ren CH, Li L, et al. Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster. Genomics 2006; 88:163-72.

GLIPR1 Antibody: GLIPR, RTVP1, CRISP7, GLIPR, Glioma pathogenesis-related protein 1, Protein RTVP-1, GliPR 1

ELISA, WB, IF

110825980

Liquid