GLIPR1L1 Antilichaam

The GLIPR1-like 1 protein (GLIPR1L1) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (1) . GLIPR1L1 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (2) . GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3) . Unlike GLIPR1, GLIPR1L1 is expressed primarily in the testis and is thought to be involved in the binding of sperm to the oocyte complex (4) .

256710

Q6UWM5

NP_689992

Human

Unconjugated

Primary Antibodies

Homeostasis

GLIPR1L1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1313 - Human Testis Tissue Lysate

1 mg/mL

GLIPR1L1 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

GLIPR1L1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

GLIPR1L1 antibody is human specific. At least two isoforms of GLIPR1L1 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

GLIPR1L1

Cat. No. 11-701 - Human Testis Tissue Slide

GLI pathogenesis-related 1 like 1

Homo sapiens

Ren C, Ren CH, Li L, et al. Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster. Genomics 2006; 88:163-72.

Murphy EV, Zhang Y, Zhu W, et al. The human glioma pathogenesis-related protein is structurally related to pathogenesis-related proteins and its gene is expressed specifically in brain tumors. Gene 1995; 159:131-5.

Ren C, Li L, Yang G, et al. RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer. Cancer Res. 2004; 64:969-76.

Gibbs GM, Lo JC, Nixon B, et al. Glioma pathogenesis-related 1-like 1 is testis enriched, dynamically modified, and redistributed during male germ cell maturation and has a potential role in sperm-oocyte binding. Endocrinology 2010; 151:2332-42.

GLIPR1L1 Antibody: PRO7434, ALKN2972, GLIPR1-like protein 1

ELISA, WB, IHC-P, IF

22749527

Liquid