GLP1R Konijn pAb (APR28328N)
Gecertificeerd

GLP1R Konijn pAb (APR28328N)

Catalog #: APR28328N-01
Maat: 50 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Background

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GLP1R Rabbit pAb (APR28328N) .

Synonyms

GLP1R; GLP-1; GLP-1-R; GLP-1R

Gene ID

2740

UniProt

P43220

Cellular Locus

Cell membrane, Multi-pass membrane protein

Applications

WB (Rattus norvegicus, Homo sapiens, Mus musculus) IHC (Mus musculus)

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 53kDa Observed MW: 53kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2740

Uniprot URL

https://www.uniprot.org/uniprot/P43220

AA Sequence

GPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNS

Beschrijving

GLP1R Konijn pAb (APR28328N) Beschikbaar in 50 µL. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamGLP1R Konijn pAb (APR28328N)
Categorie
Beschikbare grootte50 µL
CatalogusnummerAPR28328N-01