GLRB Antilichaam

This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

2743

P48167

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 23-265 of human GLRB (NP_000815.1) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 58kDa

IgG

WB: 1:1000 - 1:2000

GLRB

NCI-H460

HT-1080

THP-1

Mouse brain

Mouse liver

Glycine receptor subunit beta

Homo sapiens

Glycine receptor subunit beta, Glycine receptor 58 kDa subunit, GLRB

WB

Liquid