GLTPD1 Recombinant eiwit

Source : Escherichia Coli. GLTPD1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) and having a molecular mass of 26.8kDa. GLTPD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glycolipid Transfer Protein Domain Containing 1 (GLTPD1) belongs to the GLTP family. GLTPD1 mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. GLTPD1 is essential for normal structure of the Golgi stacks. In addition, GLTPD1 is able to bind phosphoceramides with a diversity of aliphatic chains, however GLTPD1 has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains. Moreover, GLTPD1 is inefficient with phosphoceramides which contains lignoceryl (C24:0) . GLTPD1 participates in the regulation of the cellular levels of ceramide-1-phosphate, and in that way contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid.

Ceramide-1-Phosphate Transfer Protein||Glycolipid Transfer Protein Domain-Containing Protein 1||Glycolipid Transfer Protein Domain Containing 1||GLTP Domain-Containing Protein 1||GLTPD1||GLTPD1||Ceramide-1-phosphate transfer protein||CPTP.

Greater than 90.0% as determined by SDS-PAGE.

GLTPD1 protein solution (0.25mg/mL) containing Phosphate buffered saline (pH7.4), 50% glycerol and 1mM DTT.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please avoid freeze thaw cycles.

MGSSHHHHHH SSGLVPRGSH MGSMDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLG TIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHW LQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRA VTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAE HSLLDLP.