GLUD1 Antilichaam - N-terminaal gebied: Biotine (ARP45708 P050-Biotine)

Glutamate dehydrogenase 1

GDH, GDH1, GLUD

2746

P00367

NP_005262

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Sheep, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human GLUD1

L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate. Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification. L-glutamate dehydrogenase (EC 1.4.1.3) has a central role in nitrogen metabolism in plants and animals. Glutamate dehydrogenase is found in all organisms and catalyzes the oxidative deamination of 1-glutamate to 2-oxoglutarate (Smith et al., 2001 [PubMed 11254391]) . Glutamate, the main substrate of GLUD, is present in brain in concentrations higher than in other organs. In nervous tissue, GLUD appears to function in both the synthesis and the catabolism of glutamate and perhaps in ammonia detoxification (Mavrothalassitis et al., 1988 [PubMed 3368458]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-51 M20867.1 1-51 52-3120 BC112946.1 16-3084

FUS; UBC; DCP2; KLHL29; SUMO1; NEDD8; LSM1; ILK; CDK5; VTN; SEC62; STAT5A; ORM1; HPX; NR4A1; FN1; CRP; ASGR2; CUL3; ELAVL1; EBNA-LP; HDAC5; ICT1; GLUD1; DYNLL1; GOT2

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

GLUD1 is strongly supported by BioGPS gene expression data to be expressed in HT1080

0.5 mg/ml

Cow: 86%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rat: 100%; Sheep: 86%; Yeast: 86%; Zebrafish: 83%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

56kDa

Kawajiri, M., (2006) Pediatr. Res. 59 (3), 359-364

Wet Ice

558

GLUD1

GLUD1

Rabbit

Glutamate dehydrogenase 1, mitochondrial

NM_005271

EGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF