GLUL Monoklonale Antilichaam

GLUL Monoclonal Antibody: Glutamate ammonia ligase (GLUL) belongs to the glutamine synthetase family and catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. GLUL is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Recent studies have suggested that elevated levels of GLUL may be an early marker for hepatocellular carcinoma.

2752

NP_002056

Human, Mouse, Rat

Mouse monoclonal GLUL antibody was raised against a 15 amino acid peptide near the amino terminus of human GLUL.

Unconjugated

Primary Antibodies

Homeostasis

GLUL Monoclonal Antibody is affinity chromatography purified via peptide column.

Cat. No. 1303 - Human Brain Tissue Lysate

1 mg/mL

GLUL Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

GLUL Monoclonal antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Predicted: 41 kDa

IgG1

GLUL antibody can be used for detection of GLUL by Western blot at 0.5 - 1 μ g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ g/mL. For immunofluorescence start at 20 μ g/mL.

GLUL

Glutamate-ammonia ligase

Homo sapiens

Wang Y, Kudoh J, Kubota R, et al. Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24.

Long J, Lang ZW, Wang HG, et al. Glutamine synthetase as an early marker for hepatocellular carcinoma based on proteomic analysis of resected small hepatocellular carcinomas. Hepatobiliary Pancreat. Dis. Int. 2010; 9:296-305.

GLUL Monoclonal Antibody: Glutamate ammonia ligase, glutamine synthase, glutamate decarboxylase, GLNS, GS, PIG43, PIG59, cell proliferation-inducing protein 59

ELISA, WB, IHC-P, IF

19923206

Liquid