Glutathion geoxideerd-13C4,15N2

Glutathione oxidized-13C4,15N2 is the 13C and 15N labeled Glutathione oxidized. Glutathione oxidized is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

1416898-83-3

L-Glutathione oxidized-13C4,15N2; GSSG-13C4,15N2; Oxiglutatione-13C4,15N2

12352211

Endogenous Metabolite; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Metabolic Disease

99.80

10 mM in DMSO|H2O : 250mg/mL (ultrasonic)

OC([C@@H](N)CCC(N[C@@H](CSSC[C@@H](C([15NH][13CH2][13C](O)=O)=O)NC(CC[C@H](N)C(O)=O)=O)C([15NH][13CH2][13C](O)=O)=O)=O)=O

C16 13C4H32N4 15N2O12S2

618.59

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Nur E, et al. Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes. Biochim Biophys Acta. 2011 Nov;1812 (11) :1412-7.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-D0844S/Glutathione-oxidized-13C4-15N2-SDS-MedChemExpress.pdf

Isotope-Labeled Compounds

No Development Reported