Glutathionmonoethylester

Glutathione monoethyl ester is a glutathione derivative that can protect motor neuron cells NSC-34 from pathology damage caused by mutations in TDP-43, including reducing aggregation formation, nuclear clearance, reactive oxygen species generation, and cell death[1].

118421-50-4

12352211

H315-H319-H335

Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Neuroscience-Neuromodulation

Neurological Disease

OC(CNC([C@H](CS)NC(CC[C@H](N)C(O)=O)=O)=O)=O.CCO

C12H21N3O6S

335.38

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

[1]Tong Chen, et al. Glutathione monoethyl ester prevents TDP-43 pathology in motor neuronal NSC-34 cells. Neurochem Int. 2018 Jan:112:278-287.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W392413/

Reference compound1

No Development Reported