Glyco-3ß,5α,6ß -trihydroxycholaanzuur (NPCBA2)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Glyco-3ß,5α,6ß -trihydroxycholanoic acid (NPCBA2) is a bile acid which accumulates preferentially in Niemann-Pick C (NPC) patients. Glyco-3ß,5α,6ß -trihydroxycholanoic acid is a biomarker for the early diagnosis of Niemann-Pick C disease[1].
1917340-40-9
12352211
Endogenous Metabolite
Metabolic Enzyme/Protease
Neurological Disease
C[C@@]12[C@]3([H])[C@](C[C@H]([C@]1(C[C@H](CC2)O)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(NCC(O)=O)=O)C
C26H43NO6
465.62
[1]Mazzacuva F, et al. Identification of novel bile acids as biomarkers for the early diagnosis of Niemann-Pick C disease. FEBS Lett. 2016 Jun;590 (11) :1651-62.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N15891/
Natural Products
No Development Reported
Beschrijving
Glyco-3ß,5α,6ß -trihydroxycholanoic acid (NPCBA2) is a bile acid which accumulates preferentially in Niemann-Pick C (NPC) patients. Glyco-3ß,5α,6ß -trihydroxych
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