Glyoxal-d2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Glyoxal-d2 is the deuterium labeled Glyoxal. Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced glycation end-products (AGEs). Glyoxal is promising for research of oxidative stress-related diseases (such as atherosclerosis, cataract, Alzheimer's disease), and the formation of calcium oxalate kidney stones[1][2].
16355-99-0
12352211
Drug Metabolite; Isotope-Labeled Compounds
Metabolic Enzyme/Protease; Others
Metabolism-protein/nucleotide metabolism
Metabolic Disease
O=C([2H])C([2H])=O
C2D2O2
60.05
[1]Shangari N, O'Brien PJ. The cytotoxic mechanism of glyoxal involves oxidative stress. Biochem Pharmacol. 2004 Oct 1;68 (7) :1433-42.|[2]Lange JN, et al. Glyoxal formation and its role in endogenous oxalate synthesis. Adv Urol. 2012;2012:819202.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-Y0785S/
Isotope-Labeled Compounds
No Development Reported
Beschrijving
Glyoxal-d2 is the deuterium labeled Glyoxal. Glyoxal is a cytotoxic α-oxoaldehyde. Glyoxal induces cell damage and promotes protein glycation to form advanced g
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