Glypican-3/GPC3, Human (S495A, S509A, HEK293, His)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. Glypican-3/GPC3 Protein, Human (S495A, S509A, HEK293, His) is the recombinant human-derived Glypican-3/GPC3 protein, expressed by HEK293, with C-His labeled tag.
Glypican-3/GPC3 Protein, Human (S495A, S509A, HEK293, His), Human, HEK293
12352202
2719 (Gene_ID) P51654-1 (Q25-H559) (Accession)
Approximately 28-32 kDa, 42-45 kDa and 65-75 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Room temperature in continental US; may vary elsewhere.
Recombinant Proteins
Beschrijving
The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes.
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