Glypican-3/GPC3, menselijk (R355A, R358A, HEK293, Fc)

The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. Glypican-3/GPC3 Protein, Human (R355A, R358A, HEK293, Fc) is the recombinant human-derived Glypican-3/GPC3 protein, expressed by HEK293, with C-hFc labeled tag.

Glypican-3/GPC3 Protein, Human (R355A, R358A, HEK293, Fc), Human, HEK293

12352202

2719 (Gene_ID) P51654-1 (Q25-H559, R355A, R358A) (Accession)

Approximately 230 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

Room temperature in continental US; may vary elsewhere.

Recombinant Proteins