GM2A Antilichaam - N-terminaal gebied: Biotine (ARP46007_P050-Biotine)

GM2 ganglioside activator

SAP-3, GM2-AP

2760

P17900

NP_000396

Human, Guinea Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human GM2A

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

ELAVL1; UBC; HEXA; GPLD1; PLD2

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Guinea Pig: 83%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21

Wet Ice

193

GM2A

GM2A

Rabbit

Ganglioside GM2 activator

NM_000405

SWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDL