GMPS Antilichaam - Middengebied: FITC (ARP48619_P050-FITC)

Guanine monphosphate synthetase

GATD7

8833

P49915

NP_003866

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human GMPS

In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

UBC; SUMO2; SUMO3; TNRC6B; SUMO1; NEDD8; COASY; EFHD2; PPME1; TSTA3; RCN1; RAB1A; PSMD5; PNP; MTAP; ENO2; FBXO6; AGPAT2; VCAM1; ITGA4; FN1; APRT; AHCY; CUL3; SIRT7; SUMO4; USP7; DDA1; PRKAG2; BABAM1; TCEAL1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

GMPS is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

77kDa

Guo, D., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1308-1318

Wet Ice

693

GMPS

GMPS

Rabbit

GMP synthase [glutamine-hydrolyzing]

NM_003875

VCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA