GNE-7883
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2648450-42-2
YAP
Hippo
C28H29FN6O2
GNE-7883 is a potent and allosteric small-molecule inhibitor of pan-TEAD, that allosterically blocks the interactions between YAP/TAZ and all human TEAD paralogs through binding to the TEAD lipid pocket. It effectively reduces chromatin accessibility at TEAD motifs, suppresses cell proliferation in a variety of cell line models and achieves strong antitumor efficacy in vivo. Furthermore, it effectively overcomes KRAS G12C inhibitor resistance.
Beschrijving
GNE-7883 Beschikbaar in 25 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Gabbr1 Mouse Monoclonal Antibody [Clone ID: S93A-49]
TA326530
100 µg
BSA-Myc/DDK Control Protein
AR100025
50 µL
NH-6
ABC-TC0826
1 Vial
Anti-TAT (Thrombin-antithrombin) Antibody
ABS 014-22-1
1000 µL
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg
CD35 (CR1) mouse monoclonal antibody, clone J3D3, Azide Free
BM2364
0.2 mg
Anti-KIR2DL1 (Rabbit, Monoclonal, Rabbit mAb)
A115392
100 µL
Stains-all
03943-5
5 g
Recent gezochte producten
Tumor Endothelial Marker 7 Precursor (TEM7) (PLXDC1) Mouse anti-Human Monoclonal (aa411-427) (197C193) Antibody
GWB-2130E1
0.05 mg
Gabbr1 Mouse Monoclonal Antibody [Clone ID: S93A-49]
TA326530
100 µg
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) NUP93A Polyclonal Antibody
MBS7180660
Inquire
Rabbit anti-Mus musculus (Mouse) Unc93a Polyclonal Antibody
MBS7198986
Inquire
Mouse Anti- CRISPR/Cas9 [7A9-3A3]
MBS375383-01
0.1 mg
Anti-CD93 Antibody (APC), Mouse Monoclonal
MBS8106535-01
25 Tests
Anti-CD93 Antibody (FITC), Mouse Monoclonal
MBS8106536-01
25 Tests
Anti-CD93 Antibody (PE), Mouse Monoclonal
MBS8106537-01
25 Tests