GOLGA5 Antilichaam

GOLGA5 Antibody: GOLGA5 (Golgi autoantigen, subfamily A, member 5), also known as GOLGA84, RFG5 (RET-fused gene 5 protein) or GOLIM5, is a ubiquitously expressed single-pass type II coiled-coil membrane protein that is involved in maintaining Golgi structure (1) . It is localized to the Golgi apparatus and predominantly found on membranes at the cis side of the Golgi stack (1,2) . As a mitotic phosphoprotein, GOLGA5 binds to active Rab 1 and associates with CASP (an isoform of CDP) in a golgin-tethering complex that is believed to play a role in intra-Golgi retrograde transport (3,4) . Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC) (5) .

9950

Q8TBA6

NP_005104

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Homeostasis

GOLGA5 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1313 - Human Testis Tissue Lysate

1 mg/mL

GOLGA5 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

GOLGA5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

GOLGA5 antibody is human, mouse and rat reactive. Two isoforms of GOLGA5 exist due to alternative splicing events.

GOLGA5

Cat. No. 11-701 - Human Testis Tissue Slide

Golgin A5

Homo sapiens

Bascom RA, Srinivasan S, Nussbaum RL. Identification and characterization of golgin 84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain. J. Biol. Chem. 1999; 274:2953-62.

Diao A, Rahman D, Pappin DJ, et al. 2003. The coiled-coil membrane protein golgin 84 is a novel Rab effector required for Golgi ribbon formation. J. Cell Biol. 2003; 160:201-12.

Malsam J, Satoh A, Pelletier L, et al. Golgin tethers define subpopulations of COPI vesicles. Science 2005; 307:1095-8.

Sohda M, Misumi Y, Yamamoto A, et al. Interaction of Golgin-84 with the COG complex mediates the intra-Golgi retrograde transport. Traffic 2010;11:1552-66.

GOLGA5 Antibody: RFG5, GOLIM5, ret-II, RETII, RFG5, PIG31, Golgin subfamily A member 5, Cell proliferation-inducing gene 31 protein

ELISA, WB, IHC-P, IF

30260188

Liquid