GOPC Antilichaam - middengebied: HRP (ARP56215 P050-HRP)

Golgi-associated PDZ and coiled-coil motif containing

CAL, FIG, PIST, GOPC1, dJ94G16.2

57120

Q9HD26

NP_001017408

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human GOPC

GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].

BATF; SSNA1; VTN; MYLK; HCK; FOSL2; DPYD; RPL13AP17; C17orf67; ZSCAN1; LCLAT1; FAM9B; ZBTB49; ZNF564; SPATA8; RNF183; MORN4; MYOCD; MUM1; ZNF587; SLC25A18; CCDC102B; AKIRIN1; MRPL1; SEMA4G; RNF220; FAM90A1; PID1; ZNF581; CERCAM; RHOQ; PARK7; STARD3; HSF1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

50kDa

Wolde, M., (2007) J. Biol. Chem. 282 (11), 8099-8109

Wet Ice

454

GOPC

GOPC

Rabbit

Golgi-associated PDZ and coiled-coil motif-containing protein

NM_001017408

RNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKE