Gostatine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Gostatin is an inhibitor of aspartate aminotransferase (GOT) . Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory effect on pig heart GOT, a weak inhibitory effect on wheat germ GOT and GPT, and no significant effect on glutamate dehydrogenase and glutamine synthetase. The inhibitory mechanism of gostatin is similar to substrate competitive inhibition, and aspartate has a protective effect on its inhibitory effect. Gostatin can be used to study the catalytic mechanism of GOT and its role in nitrogen metabolism[1].
Gostatine
12352005
Aminotransferases (Transaminases)
Metabolic Enzyme/Protease
Metabolism-protein/nucleotide metabolism
Metabolic Disease
OC(CC1=C(NCC(C1=O)N)C(O)=O)=O
C8H10N2O5
214.18
[1]Sawao Murao, et al. New Aspartate Aminotransferase Inhibitor (Gostatin) Produced by Streptomyces sumanensis nov. sp., NK-23. Agricultural and Biological Chemistry, Volume 45, Issue 4, 1 April 1981, Pages 1039–1041.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N15587/
Natural Products
No Development Reported
Beschrijving
Gostatin is an inhibitor of aspartate aminotransferase (GOT) . Gostatin is found in Streptomyces sumanensis nov. sp. NK-23. Gostatin has a strong inhibitory eff
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