GPHN Antilichaam

GPHN encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency.

10243

Q9NQX3

Q9NQX3

Human, Mouse

This GPHN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human GPHN.

Unconjugated

Primary Antibodies

Neuroscience

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Chicken, Rat

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

80 kDa

Rabbit Ig

GPHN

Gephyrin

Homo sapiens

Tabakoff, B., et al. BMC Biol. 7, 70 (2009)

Fritschy, J.M., et al. Trends Neurosci. 31 (5) :257-264 (2008)

Inada, T., et al. Pharmacogenet. Genomics 18 (4) :317-323 (2008)

Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

Gephyrin, Molybdopterin adenylyltransferase, MPT adenylyltransferase, Domain G, Molybdopterin molybdenumtransferase, MPT Mo-transferase, Domain E, GPHN, GPH, KIAA1385

WB, IHC-P, Flow

13431554

Liquid