GPNMB Antilichaam

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

10457

Q14956

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 22-260 of human GPNMB (NP_001005340.1) .

Unconjugated

Primary Antibodies

Cancer, Immunology, Innate Immunity

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 64kDa

IgG

WB: 1:500 - 1:2000

GPNMB

K-562

U-87MG

Mouse brain

Mouse liver

Rat brain

Glycoprotein (transmembrane) nmb

Homo sapiens

GPNMB, HGFIN, NMB

WB

Liquid