GPR110 Polyklonale Antilichaam, Cy5,5 Vervoeging

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.

PGR19; GPR110; KPG_012; hGPCR36; Adhesion G-protein coupled receptor F1; G-protein coupled receptor 110; G-protein coupled receptor KPG_012; G-protein coupled receptor PGR19; ADGRF1

266977

Q5T601

Cell membrane

Human, Mouse

51-150/910

GPR110

Cy5.5

KLH conjugated synthetic peptide derived from human G protein coupled receptor 110

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

675nm/694nm

1µg/µl

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

266977