GPR161 Polyklonale Antilichaam, FITC Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity) .
RE2; G-protein coupled receptor 161; G-protein coupled receptor RE2; GPR161
23432
Q8N6U8
Cell membrane
• Rabbit
Human
121-220/529
GPR161
• Polyclonal
• IgG
FITC
KLH conjugated synthetic peptide derived from human GPR161
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
494nm/518nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
23432
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse
Beschrijving
GPR161 Polyklonale Antilichaam, FITC Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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