GPR31 Polyklonale Antilichaam

High-affinity receptor for 12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE) . 12- (S) -HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

HETER; HETER1; 12-HETER; 12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid receptor; 12- (S) -HETE receptor; G-protein coupled receptor 31; GPR31

2853

O00270

Cell membrane

Human

121-220/319

GPR31

Unconjugated

KLH conjugated synthetic peptide derived from human G protein coupled receptor 31

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

2853