GPX1 Antilichaam

This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

2876

P07203

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 50-203 of human GPX1 (NP_000572.2) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 22kDa

IgG

GPX1

Mouse liver

Mouse kidney

Rat liver

Rat spleen

Glutathione peroxidase 1

Homo sapiens

Glutathione Peroxidase 1; GSHPx-1; Cellular Glutathione Peroxidase

WB, IF

Liquid