GR125487
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GR125487 is a highly selective and potent 5-HT4 receptor (5-HT4 receptor) antagonist with a Kd value of 0.1 nM. GR125487 has an extremely low affinity for 5-HT3 receptors (Kd > 1 μM) . GR125487 completely antagonizes the memory-promoting effect of BIMU1, and its administration alone has no significant effect on basic social memory. GR125487 can be used for the study of social olfactory memory[1].
144625-67-2
12352005
5-HT Receptor
GPCR/G Protein; Neuronal Signaling
Neurological Disease
O=C(OCC1CCN(CCNS(=O)(=O)C)CC1)C2=C(OC)NC=3C=CC(F)=CC32
C19H26FN3O5S
427.49
[1]Letty S, et al. 5-HT4 receptors improve social olfactory memory in the rat. Neuropharmacology. 1997 Apr-May;36 (4-5) :681-7.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W822786/
Reference compound1
No Development Reported
5-HT4 Receptor
Beschrijving
GR125487 is a highly selective and potent 5-HT4 receptor (5-HT4 receptor) antagonist with a Kd value of 0.1 nM. GR125487 has an extremely low affinity for 5-HT3
Specificaties
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