GRB 14 Polyklonale Antilichaam, APC-vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR) . Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Growth factor receptor-bound protein 14; GRB14 adapter protein; GRB14
2888
Q14449
Cytoplasm, Cell membrane
• Rabbit
Human
221-320/540
GRB 14
• Polyclonal
• IgG
APC
KLH conjugated synthetic peptide derived from human GRB 14
IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
650nm/660nm
1µg/µl
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
This antibody may also detect the similar protein GRB10 due to an 83% sequence similarity in the immunogen sequence.
2888
Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken, Rabbit
Beschrijving
GRB 14 Polyklonale Antilichaam, APC-vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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