GRB 14 Polyklonale Antilichaam, FITC Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR) . Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Growth factor receptor-bound protein 14; GRB14 adapter protein; GRB14
2888
Q14449
Cytoplasm, Cell membrane
• Rabbit
Human
221-320/540
GRB 14
• Polyclonal
• IgG
FITC
KLH conjugated synthetic peptide derived from human GRB 14
IF (IHC-P), IF (IHC-F), IF (ICC)
Purified by Protein A.
494nm/518nm
1µg/µl
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
This antibody may also detect the similar protein GRB10 due to an 83% sequence similarity in the immunogen sequence.
2888
Mouse, Rat, Dog, Cow, Sheep, Horse, Chicken, Rabbit
Beschrijving
GRB 14 Polyklonale Antilichaam, FITC Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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