GREM2 Antilichaam

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

64388

Q9H772

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human GREM2 (NP_071914.3) .

Unconjugated

Primary Antibodies

Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction, Stem Cell

Affinity purification

Mouse brain

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 19kDa

IgG

WB: 1:500 - 1:2000

GREM2

Gremlin 2, DAN family BMP antagonist

Homo sapiens

CKTSF1B2, DAND3, PRDC, STHAG9, gremlin-2, DAN domain family member 3, cysteine knot superfamily 1, BMP antagonist 2, gremlin 2, cysteine knot superfamily, homolog, protein related to DAN and cerberus

WB

Liquid