GRF2 (RAPGEF1) Mouse Monoclonal Antibody [Kloon ID: UMLBI140]

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) RAPGEF1 mouse monoclonal antibody, clone UMLBI140

C3G; GRF2

Homo sapiens Rap guanine nucleotide exchange factor 1 (RAPGEF1), transcript variant 2, mRNA.

2889

Q13905

Unconjugated

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

IHC 1:100~200

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

RAPGEF1

https://www.ncbi.nlm.nih.gov/gene/?term=2889

https://www.uniprot.org/uniprot/Q13905