GRK2 Antilichaam - C-terminalgebied: Biotine (ARP51966_P050-Biotine)

G protein-coupled receptor kinase 2

BARK1, ADRBK1, BETA-ARK1

156

P25098

NP_001610

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the C terminal region of human ADRBK1

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.

UBC; SUMO1; NEDD8; Rapgef3; GNAQ; FBXO25; ADRBK2; ACACA; HSP90AB1; HSP90AA1; GIT1; RASGRF1; MDM2; EPHA2; PEBP1; ADRB2; SNCA; GRM1; GNB1; KCNIP3; ARRB1; HDAC6; Nedd4; CSNK2B; PDGFRB; TPM2; GIT2; PDE6G; CCR4; AKAP12; PDCL; NCS1; MAPK3; PRKACA; CCR5; PIK3CG

Biotin

Polyclonal Antibody

WB

Affinity Purified

ADRBK1 is strongly supported by BioGPS gene expression data to be expressed in PANC1

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

79kDa

Wet Ice

689

GRK2

GRK2

Rabbit

Beta-adrenergic receptor kinase 1

NM_001619

ILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPL