GRO-beta (CXCL2)

Human GROß is a member of the C-X-C family of chemokines and promotes neutrophil and basophil chemotaxis and degranulation. GROß like GROa specifically inhibits growth factor-stimulated proliferation of capillary endothelial cells in a dose-dependent manner. Human GROß is a 7.9 kDa protein containing 73 amino acid residues.

CXCL2; GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a

2920

P19875

NP_002080.1

NM_002089.3

4q21

Human

Hamster, Human, Mouse

APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.

73

Lyophilized

7.9 kDa

E. coli