GSDME Antibody - C-terminal regio : HRP (ARP46106_T100-HRP)

Gasdermin E

DFNA5, ICERE-1

1687

A4FVA8

AAI25067

Human, Rat, Cow, Dog, Guinea Pig

The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

UBC; EGFR; PTN

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

DFNA5 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 85%; Dog: 77%; Guinea Pig: 83%; Human: 100%; Rat: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

47kDa

Wet Ice

437

GSDME

GSDME

Rabbit

Gasdermin-E

NM_001127453

AALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQR