GSK-J4
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release) . Cell permeable, ethyl ester of GSK J11. Rescues newborn pups from embryonic lethality in BRAF knockin mice which recapitulate major features of RASopathies2.
Unconjugated
Yellow waxy solid
-20°C
Beschrijving
GSK-J4 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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