GSK2656157
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent (IC50 = 0.9 nM) and selective (over 300 kinases) inhibitor of protein kinase RNA-like endoplasmic reticulum kinase (PERK) .1,2 Inhibited growth of multiple human tumor xenografts in mice. GSK2656157 has also been found to potently inhibit RIPK1 (IC50 = 69 nM) and TNF-mediated RIPK1 kinase-dependent cell death in mouse embryonic fibroblasts.3 It prevented the loss of dendritic spines and rescued memory deficits after traumatic brain injury.4 GSK2656157 also enhanced glucose-stimulated insulin secretion in a mouse model of type 2 diabetes mellitus.5
Unconjugated
White solid
-20°C
Beschrijving
GSK2656157 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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