
GSK2879552
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GSK289552 is potent, selective, and irreversible inhibitor of Lysine Demethylase 1 (LSD1) via covalent modification of the LSD1 cofactor FAD (Ki = 1.7 µM) . It is selective for LSD1 over the closely related LSD2, MAO-A, MAO-B, and the FAD dependent enzymes D-amino acid oxidase and glutathione reductase. Tested against a panel of 165 cancer cell lines, GSK2879552 inhibited the proliferation of 9 small cell lung carcinoma lines and 20 AML cell lines.
Unconjugated
White solid
-20°C
Beschrijving
GSK2879552 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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