GSK3-IN-9

GSK3-IN-9 (Compound 0713) is a selective glycogen synthase kinase 3 (GSK3) inhibitor. GSK3-IN-9 Fragile X syndrome, attention deficit hyperactivity disorder (ADHD), childhood seizure, intellectual disability, diabetes, acute myeloid leukemia (AML), autism, and psychiatric disorder[1].

748145-12-2

12352005

H302-H315-H319

GSK-3

PI3K/Akt/mTOR; Stem Cell/Wnt

Metabolism-sugar/lipid metabolism

Cancer; Metabolic Disease; Neurological Disease

CC1=C2C(N=C3CC(C)(CC(C3C2C4=CC=CC=N4)=O)C)=NN1

C18H20N4O

308.38

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

[1]Edward Scolnick, et al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1. 2016 December 29.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W773779/

Reference compound1

No Development Reported