GSK3178022
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GSK3178022 is a human IgG1 monoclonal antibody (mAb) targeting LRP6. GSK3178022 inhibits the expression of WNT target genes SP5 and AXIN2. GSK3178022 has antitumor activity in the RSPO fusion model of colorectal cancer. Recommended isotype control: Human IgG1 kappa, Isotype Control.
12352203
LPL Receptor; Wnt
GPCR/G Protein; Stem Cell/Wnt
Cancer-programmed cell death
Cancer
[GSK3178022]
[1]Jackson H, et al. Novel Bispecific Domain Antibody to LRP6 Inhibits Wnt and R-spondin Ligand-Induced Wnt Signaling and Tumor Growth. Mol Cancer Res. 2016 Sep;14 (9) :859-68.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991311/
Inhibitory Antibodies
No Development Reported
Beschrijving
GSK3178022 is a human IgG1 monoclonal antibody (mAb) targeting LRP6. GSK3178022 inhibits the expression of WNT target genes SP5 and AXIN2. GSK3178022 has antitu
Specificaties
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