GSK3B Antilichaam - C-terminalgebied: Biotine (ARP54644_P050-Biotine)

Glycogen synthase kinase 3 beta

2932

P49841

NP_002084

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human GSK3B

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]) . GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

AKT1; MAP3K4; MAPT; JUN; RNF220; HDAC4; AXIN1; SNAI2; NBR1; AURKA; UBC; axl-1; pry-1; PRKAR1A; EYA1; GSK3B; AKAP11; BTRC; CTNNB1; HECW2; PRKACA; PPP1R2; APC; FRAT1; AXIN2; GSKIP; LRP6; CSF3R; DYNLL1; VIM; FRAT2; EPB41L3; CLASP2; HSP90AA1; PPP1CA; PRUNE; N

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

GSK3B is supported by BioGPS gene expression data to be expressed in 721_B, HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

48kDa

Izumi, N., (2008) J. Biol. Chem. 283 (19), 12981-12991

Wet Ice

433

GSK3B

GSK3B

Rabbit

Glycogen synthase kinase-3 beta

NM_002093

AIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNF