
GSK583
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GSK583 is a highly selective and potent inhibitor of RIP2 kinase, IC50 = 5 nM human and IC50 = 2 nM rat.1 It also potently Inhibits isolated RPI3 kinase (IC50 = 5 nM) but is inactive against RIP3 in cellular assays due to a very low KM, ATP. GSK583 blocks NOD2 signaling by interfering with XIAP-RIP2 binding resulting in decreased cytokine and chemokine production.1,2
Unconjugated
Pale yellow solid
-20°C
Beschrijving
GSK583 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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