GSK8612
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Highly selective and potent (avg. pIC50 = 6.8 versus recombinant TBK1) inhibitor of Tank-binding Kinase-1 (TBK1) with higher affinity for unactivated TBK1. It inhibited phosphorylation of IRF3 (pIC50 = 6.0), inhibited the release of IFNa from human PBMC’s (pIC50 = 6.1), and inhibited IFNb secretion from THP-1 cells (pIC50 = 5.8 dsDNA virus, 6.3 cGAMP stilmulated cells) .
Unconjugated
Beige solid
-20°C
Beschrijving
GSK8612 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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