GSS Antilichaam, KO gevalideerd

Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

2937

P48637

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 373-474 of human GSS (NP_000169.1) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

DU145

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 54kDa

IgG

WB: 1:500 - 1:2000

GSS

K-562

293T

Mouse kidney

Mouse spleen

Mouse brain

Glutathione synthetase

Homo sapiens

Glutathione synthetase, GSH synthetase, GSH-S, Glutathione synthase, GSS

WB

Liquid