GSTO1-IN-3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GSTO1-IN-3 is a potent GSTO1-1 inhibitor with an IC50 of 0.11 μM, and shows selectivity over GSTO2-2, GSTA1-1 and GSTP1-1 (IC50 > 100 μM). GSTO1-IN-3 enhances the cytotoxicity of Cisplatin against human breast cancer cells. GSTO1-IN-3 inhibits IL-1β release in mouse bone marrow-derived macrophage (BMDM) cells. GSTO1-IN-3 attenuates inflammation in mice. GSTO1-IN-3 can be used for breast cancer and inflammation research[1].
158890-32-5
12352005
H302-H315-H318-H335
Glutathione S-transferase; Interleukin Related
Immunology/Inflammation; Metabolic Enzyme/Protease
COVID-19-immunoregulation
Cancer; Inflammation/Immunology
O=C(N1CCC(CC1)CC2=CC=CC=C2)CCl
C14H18ClNO
251.75
P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
[1]Xie Y, et al. Development of potent glutathione transferase Omega-1 inhibitors with applications in inflammation and cancer therapy. Eur J Med Chem. 2025 Dec 5;299:118072.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W615446/
Reference compound1
No Development Reported
Beschrijving
GSTO1-IN-3 is a potent GSTO1-1 inhibitor with an IC50 of 0.11 μM, and shows selectivity over GSTO2-2, GSTA1-1 and GSTP1-1 (IC50 > 100 μM). GSTO1-IN-3 enhances t
Specificaties
Recent bekeken producten
Human Sertoli Cell Complete Medium
MBS2576755-01
100 mL
Urobilinogen protein
MBS5303823-01
100 mg
AffiniPure Goat Anti-Rabbit IgG H&L, HRP conjugated
GTR17765564-01
100 µL
Pribolab® Automatic Immunoaffinity Column Purification System
HWEQ-IM 5050
1 Unit
OneTaq Hot Start 2X Master Mix with GC Buffer
NEB M0485L
500 Reactions
HyperLadder 1kb
BIO-33053
100 Lanes
MicroMolar UDP assay kit - 100 assays
MUD100K
100 Assays
MEM Amino Acids Solution (50x) w/o: L-Glutamine
P08-30100
100 mL
Recent gezochte producten
Glyoxalase I Activity Assay Kit (Colorimetric)
K591-100
100 Assays
Methylglyoxal Assay Kit (Colorimetric)
K500-100
100 Assays
Methanol Assay Kit (Colorimetric)
K898-100
100 Assays
PicoProbeTM Methylglyoxal Assay Kit (Fluorometric)
K461-100
100 Assays
Chlorine (Cl) Assay Kit (Colorimetric)
NBP3-25924
96 Tests
ATP Assay Kit (Colorimetric)
NBP3-24473
96 Tests
Alcohol Assay Kit (Colorimetric)
MBS168355-01
100 Assays
Total Thiol Assay Kit (Colorimetric)
MBS169295-01
192 Assays