GTF2I Antilichaam - middengebied: FITC (ARP58007_P050-FITC)

General transcription factor IIi

WBS, DIWS, SPIN, IB291, BAP135, BTKAP1, TFII-I, WBSCR6, GTFII-I

2969

P78347

NP_127492

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human GTF2I

GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon (s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene.

TP53; ZMYM3; PIAS2; TUBG1; TRAF6; SUMO2; SUMO3; AP2B1; DPY30; GCC1; MTUS2; MDM2; UBC; SUMO1; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; CTPS2; WARS; RPL28; RAD23B; PRPS2; PRKDC; NUCB1; METTL1; ADSL; FBXO6; UBD; CBX2; TAB2; AP4S1; CBX4; MAPK12; C4BPA; MAP3K3; SLU

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB, IHC

Affinity Purified

There is BioGPS gene expression data showing that GTF2I is expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

112kDa

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Wet Ice

998

GTF2I

GTF2I

Rabbit

General transcription factor II-I

NM_032999

INNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW