GTPBP4 Antilichaam - C-terminaal gebied: Biotine (ARP54884 P050-Biotine)

GTP binding protein 4

NGB, CRFG, NOG1

23560

Q9BZE4

NP_036473

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human GTPBP4

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

SUMO3; UBC; POP1; PNMA2; PSME3; PRKRA; SUMO1; STAU1; NEDD8; EIF6; IFRD1; AZGP1; MRTO4; KCTD2; DICER1; SUZ12; EED; RNF2; CSNK2A2; CBX8; VCAM1; FN1; ESR1; UBD; CAND1; COPS5; SIRT7; SUMO2; EIF2AK2; OAS3; tat; TP53; YWHAG; LYAR; PINX1

Biotin

Polyclonal Antibody

WB

Affinity Purified

GTPBP4 is strongly supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

74kDa

Lee, H., (2007) Mol. Cell. Biol. 27 (6), 2103-2119

Wet Ice

634

GTPBP4

GTPBP4

Rabbit

Nucleolar GTP-binding protein 1

NM_012341

MVKKAKTMMKNAQKKMNRLGKKGEADRHVFDMKPKHLLSGKRKAGKKDRR