GTS6 (TNFAIP6) (NM 007115) Humaan Recombinant eiwit

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010]

Purified recombinant protein of Human tumor necrosis factor, alpha-induced protein 6 (TNFAIP6), Tyr38-end, with N-terminal His tag, expressed in E. coli, 50ug

TSG-6; TSG6

7130

P98066

NM_007115

2q23.3

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0

Druggable Genome

26.8 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

TNFAIP6

Human

NP_009046

https://www.ncbi.nlm.nih.gov/gene/7130

https://www.uniprot.org/uniprot/P98066

https://www.ncbi.nlm.nih.gov/nuccore/NM_007115

https://www.ncbi.nlm.nih.gov/nuccore/NP_009046